Licorice-derived substance may have anti-inflammatory, anti-cancer effects —

Licorice is greater than a sweet folks both love or hate — it might play a task in stopping or treating sure forms of most cancers, based on researchers on the College of Illinois Chicago.

Gnanasekar Munirathinam and his analysis crew are finding out substances derived from the licorice plant Glycyrrhiza glabra to find out in the event that they may very well be used to forestall or cease the expansion of prostate most cancers. Munirathinam is an affiliate professor within the division of biomedical sciences on the Faculty of Drugs Rockford.

A analysis evaluate into molecular insights of a licorice-derived substance known as glycyrrhizin for stopping or treating most cancers carried out by Dr. Munirathinam and pupil researchers suggests additional analysis might result in particular brokers for scientific use.

The journal Pharmacological Analysis just lately printed the examine titled “Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights.”

“After we take a look at the analysis on the market and our personal information, it seems that glycyrrhizin and its spinoff glycyrrhetinic acid have nice potential as anti-inflammatory and anti-cancer brokers,” Munirathinam mentioned. “Extra analysis is required into precisely how these might finest be used to develop therapies, however this seems to be a promising space of most cancers analysis.”

Ought to everybody exit and eat a bunch of licorice? Most likely not, as a result of it might have an effect on blood stress, work together with sure drugs, and trigger critical antagonistic results, together with demise, when used excessively. An occasional candy deal with of licorice sweet or tea could also be higher choices till extra research can present finest harness the plant’s advantages.

“Only a few scientific trials in people have been carried out,” Munirathinam mentioned. “We hope our analysis on prostate most cancers cells advances the science to the purpose the place therapies could be translated to assist forestall and even remedy prostate and different forms of most cancers.”

Faculty of Drugs Rockford college students Rifika Jain, Mohamed Ali Hussein, Preksha Shahagadkar, Shannon Pierce and Chad Martens are co-authors of the evaluate, which was partly supported by the Nationwide Institutes of Well being (R0CA227218) and Brovember Inc.

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Supplies supplied by College of Illinois Chicago. Authentic written by Carrie Foust. Notice: Content material could also be edited for type and size.